LuxSci vs Protected Trust
Updated October 16, 2026
Healthcare organizations that email patients under HIPAA sometimes compare LuxSci and Protected Trust. Both encrypt mail and sign business associate agreements, but LuxSci is built for high-volume sending from EHR, CRM, and billing systems, while Protected Trust's Send It Secure is an Outlook add-in for staff writing one message at a time. The volume you send settles this faster than any feature.
Our analysts compared LuxSci and Protected Trust on high-volume sending, Outlook fit, system connections, rollout, and pricing, using the HIR review of each company. In the following sections, we compare the services in a table, describe which sender each fits, and note LuxSci's dated news this year.
LuxSci vs Protected Trust at a glance, October 2026
| What buyers weigh | LuxSci | Protected Trust |
|---|---|---|
| Published price | LuxSci describes volume tiers on luxsci.com. Confirm a current quote. | Packages are sold through sales. Confirm a current quote. |
| Pricing model | Subscriptions for HIPAA secure email and APIs, priced by how much you send each month. The posted tiers are aimed at mid-sized healthcare senders. | A subscription for Send It Secure email encryption, priced per seat or for the whole organization. |
| What drives cost | How much email you send each month, API use, marketing features, and support. | Seats, message volume, and compliance features. |
| Main job | High-volume HIPAA email and marketing sent from other systems through its APIs. | Encrypting the email staff write in Outlook every day. |
| Sending thousands of messages | Built for it, and scores 7.0 on high-volume sending outcomes. | Not built for bulk sending, and scores 6.8 on secure email outcomes. |
| Working inside Outlook | Sold as a hosted secure email and sending service. | An Outlook add-in, so staff keep their mailbox. Clear edge |
| Connecting other systems | APIs for EHR, CRM, and billing systems to send personalized messages. Clear edge | Built for people sending one message at a time from Outlook. |
| Getting it live | Scores 6.6, because API and system integrations take work. | Scores 6.8, as an add-in and a policy rollout. |
| Time to full value | About 5 to 13 weeks | About 5 to 11 weeks |
| What you need first | A named IT or security owner for switching over mail routing. | Compliance owner named. |
| Deal-breaker | Nobody will own DNS, mail routing, or BAA paperwork. | You only need medical device security. |
| Pricing clarity score | 6.7 | 6.7 |
| HIR overall score | 6.8, Conditional. | 6.7, Conditional. |
| Best for | Healthcare marketers and mid-sized organizations that send thousands of HIPAA-compliant emails a month from their EHR, CRM, or billing systems. | Small healthcare offices on Outlook that want to encrypt and send messages without moving their email. |
| Not a fit for | Small clinics that only need to encrypt everyday staff email. | Teams that do not work in Outlook. |
Which fits which buyer
Estimate how many patient emails you send each month.
Choose LuxSci if
- You send thousands of patient emails a month from an EHR, CRM, or billing system.
- You want APIs to personalize patient messages at scale.
- You have an IT owner for mail routing and integrations.
Choose Protected Trust if
- Your staff write patient emails one at a time in Outlook.
- You want encryption and proof of delivery without changing mailboxes.
- You are a small office without integration work planned.
Verdict
LuxSci is the right tool for organizations sending patient email in bulk from other systems. Protected Trust is the simpler choice for a small Outlook office encrypting everyday messages.
If Microsoft or Google encryption meets your needs, test that before buying either.
Where the two tools are headed in 2027 and beyond
LuxSci: LuxSci combined with Oiva Health to form a transatlantic healthcare communications group on February 12, 2026, and launched email security for mid-sized healthcare organizations on May 5, 2026.
Send a test campaign and a test staff message through each before you sign.
Methodology
Each row comes from the HIR reviews of LuxSci and Protected Trust, scored under the HIR method, and from each vendor's public pricing where it exists. Any published price for LuxSci or Protected Trust was checked on that vendor's own site on October 16, 2026.
A green check marks a clear edge for LuxSci or Protected Trust only where their review scores differ by at least 0.3 points or the two reviews show a plain difference. Rows with nothing published for either LuxSci or Protected Trust are left out, and time to full value for each adds up the rollout stages in its review.